Kleine Levin Syndrome: What Is It, What Causes It, and How Do You Treat It?

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Kleine-Levin Syndrome (KLS) is a rare Narcolepsy

  • Epilepsy
  • Multiple sclerosis
  • Tumors
  • Migraines
  • Side effects of benzodiazepines or illicit drugs
  • Conversations with your doctor will help them reach a diagnosis. They may also interview parents or others who have witnessed an episode to determine if you have KLS. 

    What Is the Treatment for Kleine-Levin Syndrome?

    Kleine-Levin Syndrome treatment aims at reducing symptoms, primarily through the use of medication.  

    For sleepiness, doctors may prescribe stimulants such as:

    Lithium is the most popular and effective drug for stabilizing someone experiencing a KLS episode and prolonging periods between episodes. Researchers speculate that the similarities between mood disorders and KLS could account for lithium’s ability to be effective in both situations. 

    Other treatments are under study.