Diabetes Drug Metformin Linked to Birth Defects in Boys

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March 28, 2022 — The drug type 2 diabetes, corroboration of these findings is urgently needed,” Germaine Buck Louis, PhD, a reproductive and perinatal epidemiologist, writes in an editorial accompanying the journal article.

Louis, the dean of the George Mason University College of Health and Human Services in Washington, DC, notes a key limitation of the research is the lack of data on how much the men in the study took the drugs they were prescribed.

Nevertheless, she writes, doctors need to help couples planning to have children weigh the risks and benefits of the father taking metformin rather than another medication.